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Features » November 11, 2003

Eli Lilly and Thimerosal

By Annette Fuentes

Thimerosal is an organic compound that is 49.6 percent ethylmercury. Eli Lilly and Co., the Indianapolis-based drug giant, developed and registered thimerosal under its trade name Merthiolate in 1929 and began marketing it as an antibacterial, antifungal product. It became the most widely used preservative in vaccines. Thimerosal cannot be used with live-cell vaccines, such as MMR (measles, mumps, rubella) or polio, because it would kill the vaccine. The only research looking into the safety of thimerosal was done in 1930 by Eli Lilly-sponsored doctors, who injected it into 22 patients with meningitis. The human experiments failed to prove that thimerosal was nontoxic. Nonetheless, researchers H.M. Powell and W.A. Jamieson published a study in September 1931 in the American Journal of Hygiene that stated thimerosal had a “low order of toxicity” for humans, without mentioning that the human subjects were ill and subsequently died. Internal Lilly documents from the time, however, revealed that the company’s researchers were worried about Merthiolate’s “burning qualities” when used on the skin. By 1935, Eli Lilly’s Jameison had further evidence of thimerosal’s toxicity when he received a letter from a researcher who had injected it into dogs and saw severe local reactions, leading him to state: “Merthiolate is unsatisfactory as a preservative for serum intended for use on dogs.”

In the 70 years since thimerosal/Merthiolate was developed, the FDA never required Eli Lilly to conduct clinical studies of its safety, despite ample evidence of its toxicity and its highly allergic properties. In fact, the FDA today still refers to the 1931 Powell and Jameison study on its Web site as indication of the “safety and effectiveness” of thimerosal as a preservative. Thimerosal/Merthiolate was widely used in over-the-counter products, including ointments, eye drops, nasal sprays and contact lens solution. In 1998, the FDA finally banned Thimerosal for use in OTC products—18 years after it began a safety review of mercury-containing products. It took another year before the CDC and the FDA would ask manufacturers to remove thimerosal from childhood vaccines. Eli Lilly stopped making Merthiolate-containing products in the mid-’80s but still profits from licensing agreements with pharmaceutical companies around the world.

Eli Lilly faces hundreds of civil lawsuits from parents who blame thimerosal for their autistic children. But the pharmaceutical giant has powerful friends in the White House and in Congress. The elder George Bush sat on Lilly’s board of directors in the 1970s, and White House Budget Director Mitch Daniels was a Lilly executive. Lilly CEO Sidney Taurel was named by President George W. Bush to the Homeland Security Advisory Council. In November 2002, Congress passed a provision, tucked into a spending measure for homeland security, to indemnify Eli Lilly from lawsuits and require families to seek compensation through the federally funded Vaccine Injury Compensation Program. It was repealed in February 2003 after public outcry. Senate Majority Leader Bill Frist (R-Tenn.) still hopes to pass a similar bill. Congressional consideration for Eli Lilly makes sense: In the 2002 election cycle, the company gave more than $1.5 million to federal candidates, with three quarters to Republicans, making it the fourth-biggest giver in the pharmaceutical industry, according to the Center for Responsive Politics. In the current election cycle, the company already has given close to $230,000 (67 percent to Republicans) to federal candidates.

Eli Lilly may be determined to avoid liability for thimerosal, but that doesn’t mean it has abandoned children with neurological problems. This year, the FDA approved Straterra, a new Eli Lilly drug for the treatment of Attention Deficit Hyperactivity Disorder. The irony that Eli Lilly profits from damaged children is not lost on parent Robert Krakow: “When Eli Lilly is promoting Straterra on TV, saying up to 10 percent of children can be helped, you realize what we are up against.”
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Annette Fuentes is a New York-based journalist who writes frequently on health and social policy issues. A contributing editor of In These Times, she is co-author with Barbara Ehrenreich of Women in the Global Factory.

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  • Reader Comments

    Yeah right. Senator Bill Frist is going to bring up a bill to help a drug company.

    All Americans know doctors and legislators work for the public good. And safeguard the ‘common man’ from dastardly diseases and unscrupulous corporations.

    Why I’ll bet right this very second there’s a legislator, a doctor and a drug company poring over data to find the next ‘cure’ and then of course the disease it fixes.

    Boy do I feel better already.

    Posted by Chris Stevens on Nov 12, 2003 at 10:55 PM


    While the medical community continues a collective chorus of denial, not a single one of them is willing to address those researchers who have been studying the toxic effects of thimerosal and knows the thousands of published articles and studies on this dangerous neurotoxin. It would seem that the statements they often present can only be described as both intellectually and medically dishonest. While they warn us about consuming 17 micrograms of fish, there is no concern about injecting infants and toddlers with a cumulative amount of over 250 micrograms of Thimerosal, what the National Institute of Environmental Health Sciences defines as “very toxic by ingestion and inhalation.  Some physicians suggest the increase in autism is the result of better diagnosis. There have been at least three studies that have said this is not the case including one in JAMA. But let’s use a little bit of common sense here. Do you really think that doctors, psychiatrists, parents and educators failed to recognize all those 8, 9, 10 year old kids who flapped their hands wildly, engaged is odd repetitive behavior, were severely intellectually challenged and WHO CAN’T TALK ? And if autism has always been around, and we are just diagnosing it better, then where are all the adult autistics? How many of you 40 and 50 year olds grew up with autistic neighbors and classmates? This epidemic is real, it is huge, and the CDC knows that thimerosal has caused it. And unfortunately, the American taxpayers will have to pay for the lifetime support of these children, estimated to be over 10 million dollars for each child affected.
      For all those MD’s who are so confident there is no risk in injecting this known neurotoxic poison in the body of child, and believes there is no evidence that the mercury in vaccines has caused an epidemic of neurodevelopmental disorders including autism, let me issue any of you a small challenge. Have the courage to debate this issue in public, we will be happy to accommodate any of you.

    A truth’s initial commotion is directly proportional to how deeply the lie was believed…When a well-packaged web of lies has been sold gradually to the masses over generations, the truth will seem utterly preposterous and its speaker, a raving lunatic. —Dresden James

    Posted by Bobbie Manning on Nov 13, 2003 at 3:56 AM

    My grandson was perfect until he received 5 immunizations at the same time 3 in one leg and 2 in another. .We noticed the chsange ie autistic symtoms soon after injections. .I have been a nurse for31 years and also gspent 2 years giving immunizations as a shot nurse. I know the vial the vaccine medicine is in needs to be rooled to distribute all the ingrediants. If the nurse or medical assistant gave those injections without rooling vial my grandson got a large dose of thermosil. This is evident in the out come of his diagnosis.The clinics, Doctors, nurses and drug manufactures are to blame and justice should be done, if these were your children you know how you would vote on the issues!!

    Posted by Bonnie Acker on Nov 14, 2003 at 8:07 AM

    I am so upset I didn’t check my spelling on previous comment. My point was, in the physicians desk reference drug book it states “you can give up to 3-4 vaccines at the same time.” Why would any nurse or doctor with their knowledge do this???? As a immunization nurse for 2 years and a nurse for 31 years I know the danger of mixing drugs, for infants and children the only reason is to save the insurance company money. I never gave more than 2 vaccines at a time. Injection sites need to be a distance away to not mix, also the vial concentrates the thermisol at the bottom. If not mixed EACH time a syringe is drawn, a child could get more than a double dose of the mercury! I’ve seen nurses grab a vial out of the fridge and draw a dose without rolling the vial.  We ned to protect the children , Therisol is still being use in some clinics. They removed rectal thermometers from the market due to danger of mercury poisoning. This is a national crisis!!!

    Posted by Bonnie Acker on Nov 14, 2003 at 8:26 AM

    As a parent of a mercury poisoned child, I would like to thank you for this article. It was only 3 years ago that we discovered this link for the labels of developmental delay, mental retardation, seizures of unknown origin, indiopathic migraines, immune dysfunction, hypothyroidism, and a host of others that plague our beautiful 18 year old. She is improving on a metal removing protocol but it has cost us our link with most of the medical mainframe as they do not acknowledge this damage. In fact, my workplace, a large university healthcare entity, is in the midst of vaccinating hundreds of my coworkers with the flu vaccine which contains 25 mcg of this neurological toxin without any thought or effort to educate about the adverse effects. Sincerely, Mary Brookhart

    Posted by M Brookhart on Nov 14, 2003 at 2:50 PM
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Appeared in the December 8, 2003 Issue
Also by Annette Fuentes
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